Publikationen

Rockel B, Schmaler T, Huang X, Dubiel W
Electron microscopy and in vitro deneddylation reveal similar architectures and biochemistry of isolated human and Flag-mouse COP9 signalosome complexes.
Biochem Biophys Res Commun 2014; 450(2):991-997.
Mathilde Feist, Xiaohua Huang, Joachim M. Müller, Beate Rau, Wolfgang Dubiel
Can hyperthermic intraperitoneal chemotherapy efficiency be improved by blocking the DNA repair factor COP9 signalosome?.
Int J Colorectal Dis 2014; 29(6):673-680.
Gummlich L, Rabien A, Jung K, Dubiel W.
Deregulation of the COP9 signalosome-cullin-RING ubiquitin-ligase pathway: mechanisms and roles in urological cancers..
International Journal of Biochemistry & Cell Biology 2013; 45:1327-1337.
Christmann M, Schmaler T, Gordon C, Huang X, Bayram O, Schinke J, Stumpf S, Dubiel W, Braus GH
Control of Multicellular Development by the Physically Interacting Deneddylases DEN1/DenA and COP9 Signalosome..
Plos Genetics 2013; e1003275
Dubiel D, Gierisch ME, Huang X, Dubiel W, Naumann M
CAND1-dependent control of cullin 1-RING Ub ligases is essential for adipogenesis..
Biochim. Biophys. Acta Mol. Cell Res. 2013; 1833(5):1078-1084.
Rozen S, Tieri A, Ridner G, Stark AK, Schmaler T, Ben-Nissan G, Dubiel W, Sharon M
Exposing the subunit diversity within protein complexes: A mass spectrometry approach..
Methods 2013; S1046-2023(12)00327-1
Xiaohua Huang, Jürgen Ordemann, Joachim M. Müller and Wolfgang Dubiel
The COP9 signalosome, cullin 3 and Keap1 supercomplex regulates CHOP stability and adipogenesis.
Biol. Open 2012; 1:705-710.
Leppert U, Henke W, Huang X, Müller JM, Dubiel W.
Post-Transcriptional Fine-tuning of COP9 Signalosome Subunit Biosynthesis is Regulated by the c-Myc/Lin28B/let-7 Pathway..
J Mol Biol. 2011;
Hannß R, Dubiel W.
COP9 signalosome function in the DDR..
FEBS Lett. 2011;
Schmaler T, Dubiel W.
Control of Deneddylation by the COP9 Signalosome..
Subcell Biochem. 2010; :57-68.
Braumann C, Guenther N, Loeffler LM, Dubiel W.
Liver metastases after colonic carcinoma--palliative chemotherapy plus curcumin..
Int J Colorectal Dis 2009; 24(7):859-60.
Huang X, Langelotz C, Hetfeld-Pechoc BK, Schwenk W, Dubiel W.
The COP9 signalosome mediates beta-catenin degradation by deneddylation and blocks adenomatous polyposis coli destruction via USP15..
J Mol Biol. 2009; 391(4):691-702.
Dubiel W.
The COP9 signalosome-cyclosome connection..
Cell Cycle. 2009; 8(14):2139-40.
Dubiel W.
Resolving the CSN and CAND1 paradoxes..
Mol Cell. 2009; 35(5):547-9.
Hetfeld BK, Peth A, Sun XM, Henklein P, Cohen GM, Dubiel W.
The COP9 signalosome-mediated deneddylation is stimulated by caspases during apoptosis..
Apoptosis 2008; 13(2):187-95.
Braumann C, Tangermann J, Jacobi CA, Müller JM, Dubiel W.
Novel anti-angiogenic compounds for application in tumor therapy - COP9 signalosome-associated kinases as possible targets..
Mini Rev Med Chem 2008; 8(5):421-428.
Neuss H, Huang X, Hetfeld BK, Deva R, Henklein P, Nigam S, Mall JW, Schwenk W, Dubiel W.
The ubiquitin- and proteasome-dependent degradation of COX-2 is regulated by the COP9 signalosome and differentially influenced by coxibs..
J Mol Med 2007; 85(9):961-70.
Peth A, Berndt C, Henke W, Dubiel W.
Downregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stability..
BMC Biochem 2007; 8(27)
Ismail M, Henklein P, Huang X, Braumann C, Rückert RI, Dubiel W.
Identification of HIV-1 Tat peptides for future therapeutic angiogenesis..
Eur J Haematol 2006; 77(2):157-65.